Binoj Joseph Matthew

Dr. Binoj Joseph Matthew is an established Northern California health care practitioner who serves as physician with Wellnite, Inc., and focuses on medication management and care for chronic conditions. With a background in biotechnology, Dr. Binoj Joseph Matthew holds three U.S. patents in the areas of molecular genetics and molecular biology.

The ongoing coronavirus threat has resulted in a major worldwide ramp up in these medical research areas. One promising approach for a Covid-19 vaccine candidate is that undertaken by Inovio Pharmaceuticals and Beijing Advaccine Biotechnology. INO-4800 builds on vaccine trials already underway for MERS, a closely related coronavirus. Now in preclinical phases prior to human testing, it takes a “DNA vaccine” approach in sending synthetic genes to the patient’s cells that will potentially boost the immune response.

Another ongoing effort led by Moderna and the National Institute of Allergy and Infectious Diseases centers on an mRNA technology approach. Scheduled to enter phase I human trials soon, this involves injecting genetic code snippets into the patient’s muscle. This is designed to prod the muscle cells into production of the viral protein, which then spurs the immune system to fight back against the virus.

A third approach involves Sanofi Pasteur and the U.S. Biomedical Advanced Research and Development Authority. Rather than injecting a viral protein into the patient’s body, this approach centers on manufacturing a version of the coronavirus protein. This strategy has already been used successfully to create a flu vaccine, though it is expected to take some time for the drug to reach clinical trial stages.

A resident of Fresno and San Francisco, California, Dr. Binoj Joseph Matthew is a physician with significant experience in healthcare administration. Dr. Binoj Joseph Matthew is also the holder of three molecular genetics biotechnology patents and possesses more than ten years of experience in biomedical research.

New discoveries are consistently emerging in the field of biomedical research. Three recent innovations in this area are discussed below.

Genome editing of genetic sequences called CRISPR’s (clustered, regularly interspaced, short palindromic repeats) is enabling scientists to permanently alter genes in organisms and living cells. By modifying CRISPR’s, scientists are working toward being able to correct mutations within the human genome to treat diseases of genetic origin.

The development of cancer treatments using nanobots, devices composed of single-strand DNA, are underway. These nanobots can be modified into specific structures and shapes and used for certain purposes such as helping a drug reach its targeted location in the body. Some of these microscopic DNA robots can even be used to repair tissue and detect cancer.

Bio-absorbable devices that can be placed anywhere in the body and which will eventually dissolve are currently being designed by biomedical engineers and scientists. These devices assist doctors in measuring changes such as temperature and pressure in vital organ tissues without the need for invasive measures such as surgery.

Binoj Joseph Matthew

Three Distinct Approaches to Creating a Covid-19 Vaccine

Three Emerging Innovations in Biomedical Research